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Influence of maternal and placental factors on newborn body composition

Journal of Paediatrics and Child Health Feb 19, 2020

Dissanayake HU, Anderson L, McMullan RL, et al. - Researchers conducted this cross-sectional study to ascertain if maternal features, placental size or histological chorioamnionitis was correlated with newborn body composition, and to determine if placental weight can mediate the relationship between maternal prepregnancy weight and age with newborn body composition. This investigation was carried out at Royal Prince Alfred Hospital, Sydney, Australia. The sample consisted of 136 healthy, singleton, term-born newborns. Maternal factors related to newborn fat mass and fat-free mass varied, showing that different mechanisms control fat mass and fat-free mass. According to mediation analysis, placental weight partly mediates the relationship of maternal factors with newborn body composition. No association was found between histological chorioamnionitis and newborn body composition.
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