Carella M, Tran G, Bonhomme VL, et al. - Researchers focused on the impact of regional scalp block (SB) on hemodynamic stability during the noxious events of supratentorial craniotomies and total intravenous anesthesia, its impact on intraoperative anesthetic agents’ use, as well as its impact on postoperative pain control. This analysis involved 60 patients scheduled for elective craniotomy (CR). At the time of scalp block performance (Baseline), as well as 0, 1, 3, and 5 minutes following skull-pin fixation, skin incision, CR, and dura-mater incision, experts recorded mean arterial blood pressure, heart rate, SE (state entropy of the electroencephalogram), and propofol and remifentanil effect-site concentrations. Findings revealed that not only improvement in hemodynamic control during noxious events was afforded by SB in supratentorial craniotomies, but also it conferred adequate and prolonged postoperative pain control vs placebo.