Barrio J, et al. - This study assessed the impact of moderate versus deep neuromuscular blockade (NMB) on surgical conditions during low-pressure pneumoperitoneum (8 mm Hg) laparoscopic cholecystectomy (LC). Also, the comparability of the surgical conditions was investigated during low-pressure pneumoperitoneum LC performed with deep NMB versus standard-pressure pneumoperitoneum (12 mm Hg) LC. Findings demonstrated that NMB depth was not decisive neither in the improvement of surgical conditions nor in the completion of low-pressure pneumoperitoneum LC performed by experienced surgeons. Notably, irrespective of the depth of NMB, with a standard-pressure versus low-pressure pneumoperitoneum with deep NMB, surgical conditions were considered better.