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Influence of comorbidity on survival after out-of-hospital cardiac arrest in the United States

Resuscitation Oct 19, 2019

Pasupula DK, et al. - Researchers examined how survival rate is correlated with Elixhauser Comorbidity Index (ECI) among individuals suffering an out-of-hospital cardiac arrest (OHCA) in the United States. From the US National Emergency Department Sample dataset, they identified 1,282,520 (16.4%, survived-to-discharge) weighted observations presenting primarily after OHCA in the US between January 1, 2006, to December 31, 2015. They computed the odds ratio (OR) via performing logistic regression analysis with twenty-nine ECIs as predictor variables, after controlling for age and gender. Outcomes suggest a greater survival-to-discharge rate among OHCA patients with higher ECI, illustrating “comorbidity paradox” in the US. For ECI, the adjusted OR of 1.31 was evident. Among shockable and non-shockable rhythm, they observed a percentage change in the survival rate of 5.6% and 1.04%, respectively, with a unit increase in ECI.
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