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Inferior adrenal artery PI in fetuses with IUGR: Value indicating early blood redistribution and steroidogenic response

Journal of Clinical Endocrinology and Metabolism Sep 23, 2020

Xu R, Zhu Z, Tang W, et al. - Researchers conducted this prospective cross-sectional study to describe the inferior adrenal artery (IAA) pulsatility index (PI) in intrauterine growth-restricted (IUGR) fetuses without brain sparing. The sample consisted of 23 IUGR fetuses with a normal Doppler cerebroplacental ratio and 23 normal controls. Using routine transabdominal Doppler ultrasound, the PI of the IAA was recorded. According to results, IAA-PI was significantly lower in IUGR fetuses compared with normal controls. Increased adrenal gland blood flow with concomitant increases in ACTH and F levels have been noted in IUGR fetuses. IAA-PI is useful for determining early blood redistribution and may be useful in assessing the steroidogenic response in high-risk pregnancies.

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