Frawley G, et al. – A retrospective analysis was performed of data previously gathered during dose–response studies of levobupivacaine and ropivacaine spinal anesthetics, in order to investigate possible gender differences in the ED50 and ED95 of local anesthetics used for infant spinal anesthesia. There was no evidence that sex differences occur at the ED50 dose range or at the clinically relevant ED95 dose. Spinal anesthetic dose was not needed to be modified for infant girls.