Ayala M, et al. - Researchers demonstrated the relationship between gene expression and exfoliation in unilateral glaucoma cases. They included patients who were suffering from exfoliative glaucoma in one eye, meanwhile the other eye was healthy and used as a control. Eyes with and without exfoliative glaucoma demonstrated no difference in gene expression. Seemingly exfoliative glaucoma was a bilateral disease, even though the phenotype is not always clinically present.