Pabla BS, et al. - Via searching MEDLINE and EMBASE databases from January 1980 to January 2019, researchers determined the risk of gastric cancer [third-leading cause of cancer death worldwide] in immigrants from high-incidence regions to low-incidence regions (Western Europe, Australia, Brazil, Canada, Israel, and the United States). Thirty-eight cohort studies were identified that met the criteria for inclusion. Data reported that the pooled standardized incidence ratios for immigrants with all types of gastric cancer were 1.66 for men and 1.83 for women. Based on a comprehensive systematic review and meta-analysis, immigrants from regions with a high incidence of gastric cancer in regions of low incidence retain a higher risk of gastric cancer and associated mortality. Findings suggested that assessment of immigrant generation along with other risk factors could assist define populations at high risk for prevention and therapeutic measures.