Schall M, et al. - Through a cross-sectional study on elderly people, the researcher intended to investigate the semi-quantitative magnetization transfer ratio (MTR) of several structures in elderly brains and to understand the relationship between BMI and quantitative water content, T₁, T₂*. To derive (semi-)quantitative parameters in global white (WM) and gray matter (GM) and their regions, a 3D two-point method was used. There was a notable increase in T₁ in the frontal, temporal, and parietal cortices; bilateral corona radiata, right superior longitudinal fasciculus and corpus callosum, in the WM regions and T₂* in the global WM and left corona radiata, suggesting that in the elderly human brain, an elevated BMI significantly affects T₁ in WM as well as GM structures.