Increased tolerance to less extensively heat-denatured (baked) milk products in milk-allergic children
The Journal of Allergy and Clinical Immunology: In Practice Dec 13, 2017
Nowak-Wegrzyn A, et al. - This study was implemented to assess the impact of more frequent vs less frequent introduction of higher doses of more allergenic (less heat-denatured) forms of milk (MAFM) on progression to tolerance. At baseline, baked milk was tolerated by the majority of children. An association of baked-milk diets with progressive immunomodulation was also demonstrated. Progression to MAFM tolerance was reported in most of the children who consumed baked milk as a component of their diet, but there was no advantage to more frequent attempts to escalate to MAFM, per intention-to-treat analysis.
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