Wu J, et al. - By evaluating the changes in long-term relative survival, researchers used Surveillance, Epidemiology, and End Results (SEER) registries to assess treatment outcomes among children, adolescents and young adults with osteosarcoma over three decades. They analyzed osteosarcoma incidence and relative survival data from 1984-2013. They compared Kaplan-Meier curves to evaluate survival differences over three decades, age, sex, race, and socioeconomic status (SES). Results revealed that, over the three decades, overall incidence of osteosarcoma was stable, but with an improvement in survival. Males vs females had greater improved survival. The high-poverty group had significantly increased survival due to increasing improved health care system, and patients in this group having access to effective and consistent treatment without distinction.