Wang KY, Quan T, Gu A, et al. - This study was undertaken to ascertain the influence of preoperative anemia severity on 30-day postoperative complications following primary total shoulder arthroplasty (TSA). Between 2012 and 2018, researchers distinguished adult patients undergoing primary TSA in the National Surgical Quality Improvement Program database. They conducted bivariate analyses, including Chi-squared and analysis of variance, and multivariable logistical regression. A total of 13,921 patients who had undergone TSA were included in the study. There was a stepwise and approximately 2-fold increase in odds of postoperative complications for patients undergoing primary TSA, from mild anemia to moderate/severe anemia. It has been considered that patients with moderate/severe anemia should be medically optimized prior to undergoing TSA.