Song Z, et al. - In this study, researchers measured changes of insulin-like growth factor binding protein-1 (IGFBP-1) in patients with type 2 diabetes mellitus (T2D) following gastric bypass surgery. A significant improvement was noted in body weight, BMI, and waist circumference following Roux-en-Y gastric bypass (RYGB) surgery. Blood glucose, fasting blood glucose, 2-h postprandial blood glucose, and HbA1c were also noted to be significantly improved. Furthermore, they noted a higher incidence of increased serum level of IGF-binding proteins after RYGB in 6 months compared with overweight and healthy weight controls. For surgical selection and for defining the success of RYGB, IGFBP-1 may serve as part of new supplementary criteria.