Wang SH, Xu C, Tan TL., et al. - Records of 665 patients with periprosthetic joint infection (PJI) of the knee and hip who underwent two-stage exchange arthroplasty from 2000-2017 were retrospectively analyzed in order to ascertain whether postoperative glucose variability adversely influenced the outcome of two-stage exchange arthroplasty. Following two-stage exchange arthroplasty in PJI individuals, greater glucose variability was discovered to be related to heightened risks of treatment failure, reinfection, and reoperation. In comparison with people with diabetes, those who didn't have diabetes have a greater relationship between glucose variability and poor outcomes. Thus, with close surveillance and stringent postoperative glucose control, decreasing adverse outcomes may be accomplished.