Aleva FE, et al. - In a study population of stable chronic obstructive pulmonary disease (COPD) patients, researchers investigated platelet-monocyte interaction, platelet activation and reactivity and plasmatic coagulation. In this patient population, they observed increased platelet-monocyte interaction in the absence of platelet hyper-reactivity and activation of plasmatic coagulation. As anti-platelet therapy may interfere with platelet-monocyte interaction, future clinical assessment of the impacts of different anti-platelet drugs in COPD is required.