He XW, Shi YH, Liu YS, et al. - Researchers looked at the expression profiles of microRNAs in acute ischaemic stroke (AIS) patients receiving intravenous thrombolysis who were examined in this prospective cohort analysis. They also focused on the links of these profiles with the outcome in these individuals. This study included 84 AIS patients treated with intravenous thrombolysis and who had completed 3-month follow-up visits. Modified Rankin Scale scores of 0–1 and 2–6 defined favourable and unfavourable outcomes, respectively. Findings revealed unfavourable 3 month outcomes in correlation with a set of circulating microRNAs (miR-124-3p, miR-125b-5p and miR-192-5p). These microRNAs might hold clinical utility in AIS patients undergoing thrombolysis.