Increased main pulmonary artery diameter and main pulmonary artery to ascending aortic diameter ratio in smokers undergoing lung cancer screening
Clinical Imaging Feb 05, 2020
Steiger D, Han D, Yip R, et al. - Researchers intended to ascertain the prevalence of abnormally high values of these indicators of pulmonary hypertension (PH) in asymptomatic low-dose CT (LDCT) screening participants at risk of lung cancer, and determine the associated risk factors. In this study, the evaluated consecutive baseline LDCT scans of 1,949 smokers in an IRB-approved study. The main pulmonary artery diameter (MPA) and ascending aorta (AA) diameter were assessed and MPA: AA ratio was estimated. Regression analyses were applied to distinguish risk factors and CT findings of participants associated with high values. In view of the significance of PH, this study ascertained that the possible prevalence of PH is characterized by abnormally high values of MPA and of MPA: AA was greater than previously described in the general population and that pulmonary consultation be recommended for these participants.
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