Heo JH, et al. - A retrospective cohort study was conducted with data extracted from the 2008-2014 Texas Medicaid databases to determine the relationship of furosemide therapy with the incidence of bone fractures in children with congenital heart disease. They involved pediatric patients aged <12 years diagnosed with congenital heart disease, cardiomyopathy, or heart failure. A multivariate logistic regression and Cox proportional hazard model with a Kaplan–Meier plot (time-to-fracture) were used in this analysis. The findings demonstrated that in children with congenital heart disease, furosemide therapy, even with nonconsistent dosing, was linked with an increased risk of bone fractures.