Reese T, et al. - Eight hundred and ninety-nine patients with systemic lupus erythematosus (SLE) were assessed by the researchers in order to determine whether SLE had greater blood pressure visit-to-visit variability than control subjects and association of blood pressure visit-to-visit variability to a higher comorbidity burden. A significant correlation of blood pressure visit-to-visit variability with age, creatinine, CRP, triglyceride concentrations and the Charlson comorbidity score was noted in patients with SLE. Hydroxychloroquine use was related to reduced blood pressure visit-to-visit variability, whereas antihypertensives, cyclophosphamide, mycophenolate mofetil, and corticosteroids use were correlated to elevated blood pressure visit-to-visit variability. Hence, in comparison to control, patients with SLE had higher blood pressure visit-to-visit variability which, in turn, was linked to bigger Charlson comorbidity scores, several clinical features, and immunosuppressant medications. Also, hydroxychloroquine prescription had an association with lower blood pressure visit-to-visit variability.