Appiah KOB, et al. - Given that researchers of previous studies assessing blood pressure variability (BPV) in acute ischemic stroke (AIS) have shown methodological heterogeneity that could contribute to inconsistent findings, investigators analyzed study methodologies that have evaluated the long-term outcomes (≥ 7 days) of BPV post-AIS. They analyzed 19 observational studies and 1 case–control study; 7 studies were additionally included. These studies were identified from OVID Medline, Embase, The Cochrane Library, and Web of Science. Intervals between BP evaluations were reported in 24 studies. Supine BP was measured in most of the studies (n=13), and eight studies reported whether this was in the hemiparetic or unaffected arm. Overall, findings highlighted frequently observed methodological heterogeneity in studies; this was mainly attributed to incomplete study reporting. However, adverse long-term outcomes were reported in relation to increased BPV.