Yu Y, Tomlinson LA, Binenbaum G, et al. - Since early identification and timely treatment of type 1 retinopathy of prematurity (ROP) can lessen the risk of blindness, researchers sought to assess the incidence, timing and risk factors of type 1 ROP in a large, broad-risk cohort of premature infants. Of the 11,463 infants (mean birth weight (BW), 1,095 g; mean gestational age (GA), 28 weeks), 677 (5.9%, 95% CI 5.5% to 6.3%) developed type 1 ROP. Rate of type 1 ROP declined with larger GA and no infants with GA >32 weeks developed type 1 ROP. In terms of both postmenstrual age and postnatal age, type 1 ROP developed in about 6% of premature infants over wide time windows. For type 1 ROP, BW and GA are the dominant risk factors, while for type 1 ROP, other prenatal factors add marginal predictive power.