Munshi VN, et al. - Researchers retrospectively analyzed a cohort of patients undergoing first-time heart transplantation (HT), to study glycemic trends, the incidence of posttransplant diabetes mellitus (PTDM) incidence and related risk factors in these patients. They compared patients with and without pretransplant diabetes mellitus (DM) using univariate analyses. Of 152 patients who underwent HT, 109 had no pretransplant history of DM. The incidence of PTDM was estimated to be 38% by the 1-year follow-up. Heightened odds of PTDM at 1 year were reported in relation to factors such as pretransplant body mass index, insulin use during the final 24 hours of inpatient stay, mean inpatient glucose, and mean glucose in the final 24 hours prior to discharge. Significantly higher blood glucose values were detected in patients on insulin prior to discharge vs those who were not. With regard to PTDM risk in HT patients, information may be provided by inpatient glucometrics, similar to liver and kidney patients. To account for risk heterogeneity and a requirement for differential management, developing guidelines for this population is recommended.