Incidence, predictors, and midterm clinical outcomes of left ventricular obstruction after transcatheter aortic valve implantation
Catheterization and Cardiovascular Interventions May 01, 2018
Tsuruta H, et al. - Researchers examined patients who underwent transcatheter aortic valve implantation (TAVI) to determine the incidence and midterm clinical outcomes of left ventricular obstruction (LVO; defined as a peak pressure gradient >30 mm Hg) post-TAVI. Study participants were followed over 1 year, and at that point LVO was seen in 13.3% of patients. At 3-months, the highest incidence of postprocedural LVO was reported, with a decrease noted at 6 months or later. The obstruction of the outflow tract (LVOT) diameter, transvalvular velocity, and the presence of accelerated intraventricular flow at baseline were found to be related to the occurrence of LVO in a multivariate analysis. Midventricular obstruction occurred more often than LVOT obstruction. No link was evident between the occurrence of postprocedural LVO and worsened clinical outcomes.
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