Peters Y, et al. - Researchers conducted a population-based study with patients that had a first diagnosis of non-dysplastic Barrett’s esophagus (NDBE) in the Dutch nationwide registry of histopathology to determine whether the number of endoscopies that are negative for dysplasia and the persistence of NDBE over time is associated with progression to malignancy. During 2003 and 2013, 12,728 patients with NDBE were identified. It was noted that the rate of progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) was 0.68 per 100 person-years. In a population-based study in the Netherlands, there was a low risk of progression to HGD or EAC in patients with stable NDBE. In patients with persistent NDBE subgroups, surveillance intervals might be extended or even discontinued.