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Incidence of new onset type 1 diabetes in siblings of index cases with type 1 diabetes within the first 11 years in Turkish children

Journal of Paediatrics and Child Health Jan 16, 2020

Karaoglan M, et al. - Determination of T1DM incidence in siblings of children with T1DM helps prognosticate the development of new cases, therefore, investigators sought to focuses on the incidence of the disease in siblings of children with T1DM. They retrospectively screened a total of 1,497 siblings of 850 children diagnosed with T1DM between 2007 and 2018 years. They divided participants into four onset age groups such as 0–4, 5–9, 10–14 and ≥15. And identified 34 siblings diagnosed with T1DM. Finding suggests that among the siblings, in the first years following the diagnosis of an index, the incidence of T1DM can rise up to 5.8%, and the age group of 5–9 in the index and the male gender in the sibling were the most significant risk factors. The risk for siblings of children with T1DM especially increases in the first years following diagnosis in index cases were shown in findings.
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