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Incidence of lichen sclerosus and subsequent causes of death: A nationwide Finnish register study

BJOG: An International Journal of Obstetrics and Gynaecology Mar 19, 2020

Halonen P, et al. - Researchers designed a population‐based descriptive study to determine the incidence of lichen sclerosus (LS) in women. Further, they investigated the all‐cause and cause‐specific mortality of women with LS. Data on women with LS from the Finnish Hospital Discharge Register was linked with dates and causes of death from Statistics Finland and the Finnish Cancer Registry. Study population comprised all Finnish women, including 7,790 women diagnosed with LS during the period 1969–2012. The analysis revealed an increase in the incidence rate of LS adjusted for age (European Standard Population) from 14 per 100,000 woman‐years in 2003 to 22 per 100,000 woman‐years in 2010–2012. Postmenopausal women exhibited the highest age‐specific incidence rate (24–53 per 100,000) but girls aged 5–9 years also had elevated age‐specific incidence (seven per 100,000). They observed decreased overall mortality whereas there was increased mortality as a result of vulvar cancer.

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