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Incidence of hypotension according to the discontinuation order of vasopressors in the management of septic shock: A prospective randomized trial (DOVSS)

Critical Care Jun 07, 2018

Jeon K, et al. - Researchers assessed the incidence of hypotension within one hour of tapering of the first vasopressor as well as the link between serum copeptin levels and the occurrence of hypotension among patients on concomitant norepinephrine (NE) and vasopressin (AVP) recovering from septic shock. Two groups were formed: those who were assigned to taper NE first (NE group) or AVP first (AVP group). They found that a higher incidence of hypotension may be reported in association with tapering NE rather than AVP in patients recovering from septic shock who are on concomitant NE and AVP.
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