Brown MK, et al. - In this secondary analysis of a delayed cord-clamping clinical trial, researchers reviewed the current clinical practice for the range of permissive hypercapnia and determined the link between P_aCO2 and pH and adverse outcomes. They analyzed all arterial blood gas tests in the first 72 h in infants < 32 weeks gestational age. Findings suggested that a low incidence of hypocapnia and associated adverse events may be achieved via routine targeting of higher than normal P_aCO2 goals, and moderate hypercapnia may increase the risk of neurologic injury and offer little pulmonary benefit. They also found that the occurrence of hypercapnia was common.