Shiels MS, et al. - Given the increasing incidence and mortality rates of hepatocellular carcinoma (HCC) in older individuals in the United States, researchers examined the contribution of chronic infection with hepatitis C virus (HCV) and hepatitis B virus (HBV) to the recent trends in HCC incidence. HCC cases among individuals aged ≥66 years were identified using data from the Surveillance, Epidemiology, and End Results–Medicare linkage (SEER-Medicare) for the years 2001 through 2013 and the HCV and HBV status of these HCC cases were assessed using Medicare files. In this population, a total of 15,300 HCC cases occurred between 2001 and 2013. They noted a rapid increase in HCC rates among Americans aged ≥66 years during this period. Although a substantial contribution of HCV-attributable cases to this increase was evident, there was also a rise in rates of HBV-attributable and HCV/HBV-unrelated HCC during this period.