Incidence of COVID-19 and risk of diabetic ketoacidosis in new-onset type 1 diabetes
Pediatrics Sep 04, 2021
Kamrath C, Rosenbauer J, Eckert AJ, et al. - According to the findings, the local severity of the pandemic, rather than health policy measures, seems to be the primary cause of the rise in diabetic ketoacidosis and, as a result, the delayed use of healthcare during the pandemic.
The monthly relative risk (RR) for ketoacidosis in 2020 was calculated using observed and expected rates in 3,238 children with new-onset type 1 diabetes.
From April to September, and again in December, the observed vs expected frequency of diabetic ketoacidosis was significantly higher.
Each increase in the regional weekly incidence of COVID-19 by 50 cases or 1 death per 100,000 population during the first half of 2020 was associated with an increase in the RR of diabetic ketoacidosis of 1.40 and 1.23, respectively.
This link was no longer visible in the second half of 2020.
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