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Incidence of COVID-19 and risk of diabetic ketoacidosis in new-onset type 1 diabetes

Pediatrics Sep 04, 2021

Kamrath C, Rosenbauer J, Eckert AJ, et al. - According to the findings, the local severity of the pandemic, rather than health policy measures, seems to be the primary cause of the rise in diabetic ketoacidosis and, as a result, the delayed use of healthcare during the pandemic.

  • The monthly relative risk (RR) for ketoacidosis in 2020 was calculated using observed and expected rates in 3,238 children with new-onset type 1 diabetes.

  • From April to September, and again in December, the observed vs expected frequency of diabetic ketoacidosis was significantly higher.

  • Each increase in the regional weekly incidence of COVID-19 by 50 cases or 1 death per 100,000 population during the first half of 2020 was associated with an increase in the RR of diabetic ketoacidosis of 1.40 and 1.23, respectively.

  • This link was no longer visible in the second half of 2020.

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