Moon DH, et al. – This study was designed to determine the incidence of, and risk factors associated with, mandibular osteoradionecrosis (MORN) following radiation therapy (RT) for oral cavity and oropharyngeal cancers. Data revealed that the incidence of MORN was low in the modern era at a high volume academic center. Modifiable risk factors including pre–RT tooth extractions, smoking, and RT technique were associated with MORN. The risk should be minimized with appropriate dental evaluation and treatment, smoking cessation efforts, and the use of intensity–modulated RT.