Obermair A, Asher R, Pareja R, et al. - Adverse events following minimally invasive vs open radical hysterectomy for early cervical cancer were assessed. Researchers performed the Laparoscopic Approach to Carcinoma of the Cervix trial, a multinational, randomized non-inferiority trial, between 2008 and 2017. Surgeons from 33 tertiary gynecological cancer centers in 24 countries performed randomization of 631 women International Federation of Gynecology and Obstetrics 2009 stage IA1 with lymph-vascular invasion to IB1 cervical cancer; the patients underwent an either minimally invasive or open radical hysterectomy. Of these women, 536 (85%) (mean age, 46.0 years) were included in this analysis; minimally invasive radical hysterectomy was undertaken in 279 (52%) women, and open radical hysterectomy was undertaken in 257 (48%) women. Outcomes revealed that the use of minimally invasive vs open radical hysterectomy, for early cervical cancer, results in the similar overall incidence of intraoperative or postoperative adverse events.