Chuckpaiwong V, Muakkul S, Phimpho P, et al. - In this retrospective chart review, researchers sought to assess the incidence of corneal endothelial failure (CEF) and determine the risk factors of developing CEF after phacoemulsification in patients with Fuchs endothelial corneal dystrophy (FECD). The sample consisted of 2,873 patients who had phacoemulsification with intraocular lens (IOL) implantation by 3 cornea specialists. Ninety-four patients (94 eyes) diagnosed with FECD at a follow-up time of more than 6 months were involved for investigation. Data reported that the overall incidence rate of CEF after phacoemulsification was 26 per 1,000 person-years. Intraoperative complications should be regarded as a significant risk factor for the development of postoperative CEF in FECD patients. Aside from evaluating preoperative parameters, surgeons should also consider and try to avoid any intra-operative complications that may result in CEF after phacoemulsification for each individual patient.