Snyder EA, Alvarez C, Golightly YM, et al. - This study was conducted to present the incidence and progression of radiographic and symptomatic hand osteoarthritis (rHOA and sxHOA) in a large community-based cohort. Between 1999 and 2015, researchers included data from the Johnston County OA Project ( 12 ±1.2 years follow-up, age 45+). Researchers included a total of 800 individuals (68% women, 32% African American, mean age 60 years). Individuals had bilateral hand radiographs each visit, read for Kellgren-Lawrence grade (KLG) at 30 joints. We defined rHOA as KLG ≥ 2 in ≥ 1 joint. Symptomatic hand osteoarthritis was determined in a hand/joint with rHOA and self-reported symptoms or tenderness on the exam. The much-needed information about the natural history of HOA, a common and frequently debilitating condition, in the general population was provided by this study.