de Chambrun MP, Larcher R, Pène F, et al. - Researchers analyzed critically ill patients with thrombosis and antiphospholipid syndrome (APS) in this French national, multicenter, retrospective study, to determine the prognoses as well as in-hospital mortality-related factors in these patients. There were 134 patients with 152 APS episodes, who sought admission to the ICU during the study period. Age ≥ 40 years, mechanical ventilation, renal replacement therapy, and in-ICU anticoagulation were revealed as factors that showed an independent link with in-hospital mortality in the Cox multivariable model. According to the findings, in-ICU anticoagulation was identified as the only APS-specific treatment independently related to survival for all patients. Experts also identified an independent link of double therapy with better survival of patients with definite/probable catastrophic APS.