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Impulse control disorders in Parkinson disease and RBD: A longitudinal study of severity

Neurology® Aug 17, 2019

Baig F, Kelly MJ, Lawton MA, et al. - Among individuals with Parkinson's disease (PD), those with REM sleep behavior disorder (RBD), and controls, researchers outlined the occurrence, natural history, and risk factors for impulse control behaviors (ICBs). They clinically phenotyped and longitudinally screened for ICBs (with the Questionnaire for Impulsivity in Parkinson's Disease) early PD candidates (within 3.5 years of diagnosis), those with RBD, and controls. The Parkinson's Impulse Control Scale was used to evaluate the severity of the ICB. To estimate ICB prevalence and associations, multiple imputation and regression models were used. In 19.1% of patients with early PD, ICBs occur, and many endure or get worse over time. Findings suggested no association of RBD with increased ICD risk. Psychosocial drivers have an impact on the severity, including mood and support networks.

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