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Improving liver lesion characterisation using retrospective fusion of FDG PET/CT and MRI

Clinical Imaging Jan 28, 2019

Parsai A, et al. - In patients with a known primary malignancy, researchers compared retrospectively fused FDG PET/CT and MRI (PET/MRI) to FDG PET/CT and MRI for characterisation of indeterminate focal liver lesions as malignant or benign. Study participants included 70 patients with 150 indeterminate lesions after FDG PET/CT and MRI. Data reported that MRI and fused PET/MRI detected all the lesions while PET/CT detected 89.4% for detection. Compared to MRI or FDG PET/CT alone, the retrospective fusion of PET with MRI has improved characterisation of indeterminate focal liver lesions. The sensitivity, specificity, accuracy, PPV and NPV of fused PET/MRI have been higher than PET/CT and MRI for characterizing lesions as malignant.
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