Improvement of consciousness before initiating targeted temperature management
Resuscitation Jan 23, 2020
Su PI, Tsai MS, Chen WT, et al. - The percentage of postarrest patients who experienced spontaneous neurological recovery was determined and their characteristics and neurological outcomes were reported. Researchers conducted a single-center observational study enrolling a total of 540 patients with return of spontaneous circulation (ROSC) retrospectively. Assessment of the patients’ motor responses was done immediately and at 3 h following ROSC. During the 3-h interval following ROSC, change in the GCS (Glasgow Coma Score) M score (motor score) was reported in a total of 221 patients (41%), with improvement evident in 215 patients. GCS M6 at 3 h post-ROSC, but not GCS M6 at ROSC, was an independent predictor for a favorable neurological outcome. Four factors that were predictive of the GCS M6 at 3 h were in-hospital cardiac arrest, bystander CPR, the CPR duration and the initial shockable rhythm. Findings here suggest the achievement of spontaneous neurological recovery to GCS M6 within 3 h post-ROSC and a favorable neurological outcome in a significant portion of patients. Hence consideration should be given to close monitoring of GCS and later initiation of TTM in those patients with a substantial likelihood of neurological recovery.
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