Chen M, Kan J, Zhang JJ, et al. - This multicentre MOODY registry study designed to evaluate the clinical improvement after ST-elevation myocardial infarction (STEMI) percutaneous coronary intervention (PCI). They enrolled a total of 9,265 acute MI individuals registered from 24 centres, 3,142 STEMIs having a first medical contact time ≤ 12 hours and undergoing primary PCI were assigned to the Pre Group (n = 1,014, between March 1999 and October 2010) or the Post Group (n = 2128, between 2010 November and 2016 October). After primary PCI, Age, Killip Class 3, diabetes, trans-radial approach and system delay were five predictors of in-hospital death. They found that PCI for STEMI by a trained and experienced operator was correlated with a significant reduction of in-hospital death. The outcomes strongly warrant the need for developing the current system response and patient education.