Hajdu K, Kapitány A, Dajnoki Z, et al. - In the present study, the researchers sought to examine immune parameters in the blood and skin and to detect clinical and barrier changes after allergen immunotherapy (AIT) in atopic dermatitis (AD). Patients with mild-to-moderate AD (n = 14) who also had allergic rhinitis to house dust mites were chosen. All of the patients were given topical treatment, and eight of them were chosen at random for adjuvant AIT. Clinical parameters and barrier functions improved significantly in the adjuvant AIT group. There were no significant changes in blood immune parameters. Allergen immunotherapy is an effective adjuvant treatment for patients with sensitized AD. Not only does AIT improve clinical symptoms, but it also improves permeability barrier functions. APT, not SPT, should be used to detect the effect of AIT on sensitization.