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Improvement in itch and other psoriasis symptoms with brodalumab in phase 3 randomized controlled trials

Journal of the European Academy of Dermatology and Venereology Mar 12, 2018

Gottlieb AB, et al. - Authors evaluated the effect of brodalumab (an interleukin-17 receptor A antagonist) on lesional symptoms in psoriasis patients using the psoriasis symptom inventory (PSI), a validated patient-reported instrument. Compared to placebo and ustekinumab, brodalumab demonstrated rapid, robust improvements in symptoms assessed by the PSI, including itch.
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