Ayoub-Charette S, et al. - In this systematic review and meta-analysis of prospective cohort studies, researchers examined the relation of important food sources of fructose-containing sugars with incident gout. A total of 154,289 participants with 1,761 incident cases of gout were included in this analysis. Using the Grading of Recommendations Assessment, Development and Evaluation system, the overall certainty of the evidence was assessed. No reports of incident hyperuricemia were found, and no significant link between fruit intake and gout was identified. The strongest evidence was for the adverse association with intake of sugar-sweetened beverage (SSB; moderate certainty), and the weakest evidence was for the adverse association with intake of fruit juice (very low certainty) and lack of association with intake of fruit (very low certainty). The authors concluded that SSB and fruit juice intake are adversely linked to incident gout, which does not appear to extend to fruit intake.