Importance of supplemental patch testing beyond a screening series for patients with dermatitis
JAMA Nov 09, 2021
Warshaw EM, Buonomo M, DeKoven JG, et al. - In allergic contact dermatitis, proper identification of allergens and successful management can be ensured via comprehensive patch testing with more than 70 allergens, including supplemental series and personal and work materials.
This is a 17-year cross-sectional analysis of North American Contact Dermatitis Group (NACDG) data, including 43,417 patients with dermatitis who had patch testing to the NACDG screening series (65-70 allergens).
Among these, a currently relevant reaction to 1 or more supplemental allergens or substances was evident in 21.9% of patients.
Of these patients, 26% showed no currently relevant reactions to 65 to 70 screening allergens.
Significantly less probability of being male (odds ratio OR, 0.90) and/or having atopic dermatitis (OR, 0.89) was observed in patients with supplement-positive findings vs those who had supplement-negative results.
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