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Implications of blood group on lung transplantation rates: A propensity-matched registry analysis

The Journal of Heart and Lung Transplantation Sep 28, 2018

Barac YD, et al. - As blood type O lung allografts may be distributed to either blood type identical (type O) or compatible (Non-O) candidates, researchers investigated if the current organ allocation scheme in the US (based on the Lung Allocation Score) is predisposed against the allocating allografts to type O candidates, given that pool of potential donors is smaller. The OPTN/UNOS registry from May 2005 to March 2017 was retrospectively reviewed for adult candidates waitlisted for first-time isolated lung transplantation. Findings revealed that, compared to type non-O candidates, type O candidates experience lower rates of transplantation and higher rates of waitlist mortality. Findings seemed to justify further assessing regional sharing of allografts to increase transplantation rates for type O candidates so equity in access to transplants is optimized.

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