Pruller F, et al. - This study entailed quantification of aspirin- and P2Y12-mediated platelet inhibition in patients presenting with myocardial infarction and cardiopulmonary resuscitation. In resuscitated patients treated with therapeutic hypothermia, impaired aspirin- and P2Y12-mediated platelet inhibition was noted. Lowest inhibitory impacts of both drug types were seen on day 3 and patients might be at particular risk at that time. Potentially, intravenous aspirin and P2Y12 inhibitors might still supply a more predictable and stable platelet inhibition.