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Impact of underlying plaque type on strut coverage in the early phase after drug-eluting stent implantation

Coronary Artery Disease Dec 07, 2018

Kakizaki R, et al. - Researchers determined if the neointimal coverage after drug-eluting stent implantation is influenced by the underlying plaque type. Within 3 months post-implantation, assessments of 1,793 struts in 22 zotarolimus-eluting stents were carried out by means of optical coherence tomography imaging. Based on the underlying plaque type, the normal segment group, the fibrous plaque group, and the lipid plaque group were compared in terms of the percentage of struts covered by neointima. Within 3 months after zotarolimus-eluting stent implantation, less covered struts on the normal segment with thinner neointima were seen compared with struts on the lipid plaque at the stent edge. Based on findings, exercising caution was recommended when implanting longer drug-eluting stents to achieve uniform strut coverage in the early phase.
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