Bachelot A, et al. – The current study examined the effect of transition on the quality of life (QoL) in patients with congenital adrenal hyperplasia (CAH) diagnosed during childhood. Researchers reported that regular medical follow–up in adulthood was correlated with the transition between pediatric and adult care and with better QoL in adults with CAH.

Methods

• Adult patients with classic or non-classic CAH diagnosed during childhood CAH, born between 1970 and 1990, were selected from the registers of Pediatric departments belonging to the French reference center for endocrine rare disease.
• The quality of life (WHOQoL -BREF) was the primary end point .

Results

• 73 patients were incorporated into the investigation, among them 59/73 (81%) were transferred to adult endocrinologist by their pediatricians for transition.
• WHOQoL -BREF scores were similar between patients with or without transition to specialist adult services, aside from environment dimension score, which was marginally higher in CAH patients without transition.
• The results of this study revealed that CAH patients with a regular follow-up had a better physical health, psychological health and environment score and item global quality of life than the group without regular follow-up after transition.