Rao VP, et al. - Researchers performed a retrospective observational study on patients with acute infective endocarditis (IE) needing surgery in order to study the impact of the length of postoperative antibiotic therapy on results in patients who need surgery before the completion of a planned course of antibiotic therapy. The final analysis included 182 IE episodes. Postoperative antibiotic therapy was provided for a median period of 23.5 days (interquartile range 12–40 days) that lessened significantly during the period of study. Early reoperation was done on 9 (5%) patients. The primary or secondary results remained unaffected by the length of postoperative antibiotic therapy. In line with previous findings, outcomes suggest the safety of providing shorter courses of postoperative antibiotics in selected patients who require surgery during active IE without an impact on relapse of infection or survival.