Chen J, et al. – Using a multivariate Cox regression model, researchers determined how stroke recurrence is affected by smoking status. For this purpose, they analyzed patients with first-ever stroke. At baseline as well as at the first follow-up, participant smoking status was evaluated. Fatal or nonfatal recurrent stroke following 3 months of the index stroke was considered the primary end point. Overall 3,069 patients were included at baseline, including 1,331 (43.4%) nonsmokers, 263 (8.6%) former smokers, and 1,475 (48.0%) current smokers. An increase in the risk of stroke recurrence was noted among patients who smoked persistently after an initial stroke. Findings revealed a dose–response link between smoking quantity and the risk of stroke recurrence.