Impact of serum 1,5-anhydro-d-glucitol level on the prediction of severe coronary artery calcification: An intravascular ultrasound study
Cardiovascular Diabetology Jun 08, 2019
Wada H, et al. - Researchers investigated the link between 1,5-anhydro-d-glucitol (AG) levels and coronary artery plaque in 161 patients who had percutaneous coronary intervention for coronary artery disease. This study did not include patients with chronic kidney disease or glycosylated hemoglobin ≥ 7.0. Based on serum 1,5-AG levels, two groups of patients were defined (< 14.0 μg/mL vs ≥ 14 μg/mL). According to the findings, a link was evident between low 1,5-AG level (which designated postprandial hyperglycemia) and the severity of coronary artery calcification. A low 1,5-AG level was identified as a significant predictor of a greater calcification angle (> 180°) in multivariate logistic regression analysis.
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